Improved network performance via antagonism: From synthetic rescues to multi-drug combinations
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چکیده
منابع مشابه
Improved network performance via antagonism: From synthetic rescues to multi-drug combinations
Recent research shows that a faulty or sub-optimally operating metabolic network can often be rescued by the targeted removal of enzyme-coding genes - the exact opposite of what traditional gene therapy would suggest. Predictions go as far as to assert that certain gene knockouts can restore the growth of otherwise nonviable gene-deficient cells. Many questions follow from this discovery: What ...
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ژورنال
عنوان ژورنال: BioEssays
سال: 2010
ISSN: 0265-9247
DOI: 10.1002/bies.200900128